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For instance, MSCs can upregulate the expression of immunosuppressive molecules such as IDO, PGE2, and TGF-1, which play critical roles in suppressing the proliferation and function of pathogenic T cells and B cells while promoting the expansion of Tregs [55,56,57]

Liraglutide effects on glycemic control and weight in patients with type 2 diabetes Mellitus: A real-world, observational study and brief narrative review

Concern has been raised that rhGH may stimulate the immune system in KTx patients and thereby promote acute rejection episodes with the consequence of poor graft outcome in children

Ndufs2 KO adipocytes showed reduced expression of the pathways involved in fatty acid metabolism, insulin signalling, peroxisome proliferator-activated receptor (PPAR) signalling and lipolysis, along with activation of oxidative stress, inflammatory and glycolytic programmes